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1: best the supreme effort one can make; "they did their best"
2: topper, best the person who is most outstanding or excellent; someone who tops all others; "he could beat the best of them"
3: charles herbert best, best, c. h. best Canadian physiologist (born in the United States) who assisted F. G. Banting in research leading to the discovery of insulin (1899-1978)

1: best, outdo, scoop, trump, outflank get the better of; "the goal was to best the competition"

1: top-grade, unsurpassable, top-quality, prizewinning, sunday-go-to-meeting, primo, foremost, champion, optimum, high-grade, second-best, best, record-breaking, optimal, unexceeded, first, unsurpassed, superfine, unexcelled, go-to-meeting, world-class (superlative of `good') having the most positive qualities; "the best film of the year"; "the best solution"; "the best time for planting"; "wore his best suit"
2: better, advisable, best (comparative and superlative of `well') wiser or more advantageous and hence advisable; "it would be better to speak to him"; "the White House thought it best not to respond"

1: best in a most excellent way or manner; "he played best after a couple of martinis"
2: best it would be sensible; "you'd best stay at home"
3: best, better from a position of superiority or authority; "father knows best"; "I know better."